Científicos chinos han logrado modificar por primera vez a escala mundial el genoma humano usando la tecnología de manipulación genética CrisprCas9, un revolucionario método de tratamiento de los tipos de cánceres más agresivos.
La operación, que fue llevada a cabo el pasado 28 de octubre por un equipo dirigido por el oncólogo Lu You en la Universidad de Sichuan (Chengdu), al parecer, ha sido un éxito, publicó la revista Nature.
Los investigadores extrajeron células inmunes (linfocitos T) de la sangre de un paciente con cáncer de pulmón metastásico y posteriormente emplearon la técnica de modificacion genética CrisprCas9 para neutralizar el gen que codifica la proteína PD-1.
Según se había demostrado anteriormente, esta proteína suprime el sistema inmunitario, causando la propagación de tumores, reveló el canal ruso de noticias RT (Russian Today).
Los científicos modificaron las células extraídas y después las cultivaron para introducirlas nuevamente en el cuerpo humano.
La introducción de la tecnología Crispr, que es más sencilla y eficiente que otras técnicas, acelerará la carrera para la obtención de células con genes modificados en todo el mundo, auguró Carl June, especialista en inmunoterapia de la Universidad de Pennsylvania (Filadelfia) e investigadora en la materia.
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